¡3000€!

[ES]

¡Hemos conseguido la mitad de nuestro primer objetivo! Nos sentimos muy agradecidas con la respuesta que hemos recibido en los primeros 4 días de campaña. Y es que ya hemos superado los 3000€, de hecho, ¡estamos a muy poquito de alcanzar los 4000€! ¡QUE EL RITMO NO PARE!

¡¡No te pierdas nuestro vídeo de los 3000€!! https://youtu.be/Cg3oZKlFbG0

Clica aquí para seguir apoyando nuestra campaña y no te olvides de compartir para que llegue a más personas 🙂 ¡Tú eres nuestra fuerza!

¡Ah, casi se nos olvida! Ahora puedes seguirnos en Instagram también @PSanchoLab_CSC y no te olvides de nuestro Twitter @Psancholab.

[EN]

We have reached half of our first goal! We feel very grateful for the feedback we have received in the first 4 days of the campaign. We have already surpassed 3000€, and in fact, we are so close to achieve 4000€! LET THE RHYTHM GO ON!

Don’t miss out our 3000€ video! https://youtu.be/Cg3oZKlFbG0

Click here to support our campaing, and don’t forget to share so we can reach more people 🙂 You are our strengh!

Oh, we almost forgot! You can also follow us on our new Instagram account @PSanchoLab_CSC and don’t forget about our Twitter @Psancholab.

Support our research!!!

We have created a crowdfunding campaing through the Spanish platform PRECIPITA. Our goal is to get funds to support our PhD student Bea Parejo, whose contract finishes by the end of september. This means 25% of the lab!!

Our reasearch aims to understand the role of fat for pancreatic cancer aggressiveness. We have observed that the cells with high capacity of forming new tumors in the pancreas or in other organs, can acumulate and metabolize fatty acids. This makes them completely independent from the environment, since they can use their own fat stores if there are not enough nutrients around!

We aim to understand this process and find new therapies to starve these aggressive cells to death: we can either block fatty acids import from the environment or we can let them store the fat but block its metabolism. This leads to the creation of fatty cells, which cannot move and eventually die!

Check out the official video of the campaing! https://www.youtube.com/watch?v=BGyNeElL8t8&t=6s

We need your support!! Collaborate with us!!

The webpage for donations is only in Spanish, but we can guide you through the process!!

Back to life after covid-19

Hi everyone! These last months have been challeging for many of us. We´ve been so overwhelmed that we never even updated our web! This post aims to be a quick compilation of main changes happening in the lab.

I´ll little by little update this post with the following topics:

-We had the chance to spend several weeks with our visiting researcher Pilar Acedo 🙂

From left to right: Beatriz Parejo, Sarah Courtois, Pilar Acedo, Alicia Lasierra and Lorena Marchio

-Almost at the same time we said goodbye to Lorena and Jose 😦 . We will miss you soooo sooo much.

Bea, Lorena & Sarah… Cheers!!

-We had in the lab (remotely most of the time) two wonderful Msc students: Alicia and Pilar, who has joined us as a technician replacing Jose.

Clockwise: Beatriz Parejo, Alicia Lasierra, Pilar Espiau & Sarah Courtois

-We worked from home since March 16th to May 11th… and coming back felt soooooo good!! even with the masks!!

Bea, Pilar & Sarah

-We have collaborated in 2 amazing papers just published in Nature Communications: one dissecting the role of stromal FAK in cancer metabolism with Kairbaan Hodivala-Dilke (Barts Cancer Institute, London, UK) and the other describing how ISG15 contributes to mitochondrial health in pancreatic CSCs, with Bruno Sainz Jr (IIB, Madrid, Spain)

-We have some new funding coming!! This is part of the making of! Stay tunned for updated information!!

Team work-zombie survival!

Our group is commited to keep a healthy work environment and strenghen our team spirit. For that reason, we decided to go and kill some zombies at a virtual reality game!! We had loads of fun and learn a bit more about ourselves working together under a lot of pressure!! An experience to repeat soon!!

#WorldCancerDay 2020

On February 4th we celebrate World Cancer Day to raise awareness, improve education and take action. We all have a role to play in reducing the global impact of cancer!

This year’s theme is ‘I Am and I Will’, a campaing to impulse our commitment to act. We have decided to join this movement from the lab by creating a poster and a video, that we hope you enjoy! You can find the video below. Check it out!

#SinCAPA-First National Pancreatic Cancer Researchers Symposium

Better late than never!! This post is a summary of the First National Pancreatic Cancer Researchers Symposium that we organised together with Pilar Martín Duque, Roberto Pazo and Antonio Antón in Zaragoza on November 21st to celebrate the World Pancreatic Cancer Day. 124 participants (29 speakers/chairs+95 attendants) and a lot of great science concentrated in one day! Our main objective was to create a forum in which different researchers interested in pancreatic cancer can share knowledge, materials and points of view. We had great talks both from the basic and the clinical point of view.

You can find the program here:

Pilar Navarro from IMIM opened the symposium talking about interactions between tumor and stroma
Round table and discussion of the second session. From left to right: Manuel Hidalgo, Patricia Sancho, Pilar Martín-Duque, Valeria Grazú, Sonia Melo, Héctor Peinado, Julián Pardo and Jorge Adeva
Patients´perspective session chaired by Roberto Pazo. Representatives from ACANPAN and AECC, as well as a patient who shared her batle with this disease offered a different point of view of research in pancreatic Cancer.
@psancholab at the photocall stand
@psancholab at the Patio de la Infanta Building, where the symposium took place

You can find a complete summary of the activities in the simposium in the following file (in Spanish)

SEE YOU ALL NEXT YEAR!!

DOCTORAL INPhINIT FELLOWSHIPS PROGRAMME – INCOMING

We offer an exciting PhD project for the INPhINIT PhD fellowships programme from “La Caixa” Foundation. The phylosophy of the programme is the attraction of outstanding students of any nationality for a PhD in Spain or Portugal, offering them an integral formative programme in centres of research excellence.

The candidate will join a young and vibrant research group devoted to the study of pancreatic cancer metabolism, focusing on CSC-targeting therapeutic strategies. The present project involves the study of the role of lipid storage and mobilization for CSCs adaptation to the changing and challenging conditions characteristic of tumor progression and metastasis. We aim to analyze the specific role of lipid uptake, storage and mobilization for tumor progression in order to identify and validate the most effective and readily translatable CSC-targeting strategies. For that purpose, the candidate will work with PDAC patient-derived material from solid and liquid biopsies both in vitro and in vivo.

The candidate will use a broad range of cellular and molecular biology techniques, including 3D cultures of tumor-derived cells, co-culture with stromal cells, isolation of rare subpopulations by FACS sorting and metabolic/metabolomics assays, as well as in vivo experiments involving tumorigenicity and metastasis assays. We are currently collaborating with 2 different groups located in the UK, so opportunities for short stages in those labs will be available during the completion of the PhD.

Desired skills of the candidates are: MSc in any Biomedicine-related discipline, knowledge of basic cellular and molecular techniques, knowledge of cellular metabolism, and experience in cancer research.

Celebrating the #WorldCancerResearch Day at the AECC 2019 Award Ceremony

We were invited to the AECC 2019 Award Ceremony to officially receive the Worldwide Award. This ceremony takes place every year on September 24th, the World Cancer Research Day, to acknowledge the role of scientific research in the improvement on cancer patients outcomes. The public ceremony, chaired by the Spanish Queen Letizia and the president of AECC, reviewed the position of Spanish research in the cancer field in Europe.

Our lab featured during Dr. Peinado´s presentation
With the Queen Letizia

Later on, there was a private ceremony in which all the awardees were offered a personalised commemorative painting by the main representatives of the AECC.

Our first official lab meeting!!!

We welcome Jose, Sarah and Lorena!

The new academic year starts and the lab is full of people!! (well, at least it feels full for Bea and I… 😉 )From left to right: Bea (you know her already 🙂 ); Jose , our new technician; Sarah, our postdoc, and Lorena, our visiting PhD student from Prof. Giuseppe Gasparre´s group in Bologne.