We have created a crowdfunding campaing through the Spanish platform PRECIPITA. Our goal is to get funds to support our PhD student Bea Parejo, whose contract finishes by the end of september. This means 25% of the lab!!
Our reasearch aims to understand the role of fat for pancreatic cancer aggressiveness. We have observed that the cells with high capacity of forming new tumors in the pancreas or in other organs, can acumulate and metabolize fatty acids. This makes them completely independent from the environment, since they can use their own fat stores if there are not enough nutrients around!
We aim to understand this process and find new therapies to starve these aggressive cells to death: we can either block fatty acids import from the environment or we can let them store the fat but block its metabolism. This leads to the creation of fatty cells, which cannot move and eventually die!
Hi everyone! These last months have been challeging for many of us. We´ve been so overwhelmed that we never even updated our web! This post aims to be a quick compilation of main changes happening in the lab.
I´ll little by little update this post with the following topics:
-We had the chance to spend several weeks with our visiting researcher Pilar Acedo 🙂
-Almost at the same time we said goodbye to Lorena and Jose 😦 . We will miss you soooo sooo much.
-We had in the lab (remotely most of the time) two wonderful Msc students: Alicia and Pilar, who has joined us as a technician replacing Jose.
-We worked from home since March 16th to May 11th… and coming back felt soooooo good!! even with the masks!!
Our group is commited to keep a healthy work environment and strenghen our team spirit. For that reason, we decided to go and kill some zombies at a virtual reality game!! We had loads of fun and learn a bit more about ourselves working together under a lot of pressure!! An experience to repeat soon!!
On February 4th we celebrate World Cancer Day to raise awareness, improve education and take action. We all have a role to play in reducing the global impact of cancer!
This year’s theme is ‘I Am and I Will’, a campaing to impulse our commitment to act. We have decided to join this movement from the lab by creating a poster and a video, that we hope you enjoy! You can find the video below. Check it out!
Better late than never!! This post is a summary of the First National Pancreatic Cancer Researchers Symposium that we organised together with Pilar Martín Duque, Roberto Pazo and Antonio Antón in Zaragoza on November 21st to celebrate the World Pancreatic Cancer Day. 124 participants (29 speakers/chairs+95 attendants) and a lot of great science concentrated in one day! Our main objective was to create a forum in which different researchers interested in pancreatic cancer can share knowledge, materials and points of view. We had great talks both from the basic and the clinical point of view.
We offer an exciting PhD project for the INPhINIT PhD fellowships programme from “La Caixa” Foundation. The phylosophy of the programme is the attraction of outstanding students of any nationality for a PhD in Spain or Portugal, offering them an integral formative programme in centres of research excellence.
The candidate will join a young and vibrant
research group devoted to the study of pancreatic cancer metabolism, focusing
on CSC-targeting therapeutic strategies. The present project involves the study
of the role of lipid storage and mobilization for CSCs adaptation to the
changing and challenging conditions characteristic of tumor progression and
metastasis. We aim to analyze the specific role of lipid uptake, storage and
mobilization for tumor progression in order to identify and validate the most
effective and readily translatable CSC-targeting strategies. For that purpose,
the candidate will work with PDAC patient-derived material from solid and
liquid biopsies both in vitro and in vivo.
The candidate will use a broad range of
cellular and molecular biology techniques, including 3D cultures of
tumor-derived cells, co-culture with stromal cells, isolation of rare
subpopulations by FACS sorting and metabolic/metabolomics assays, as well as in
vivo experiments involving tumorigenicity and metastasis assays. We are
currently collaborating with 2 different groups located in the UK, so
opportunities for short stages in those labs will be available during the
completion of the PhD.
Desired skills of the candidates are: MSc in
any Biomedicine-related discipline, knowledge of basic cellular and molecular
techniques, knowledge of cellular metabolism, and experience in cancer
We were invited to the AECC 2019 Award Ceremony to officially receive the Worldwide Award. This ceremony takes place every year on September 24th, the World Cancer Research Day, to acknowledge the role of scientific research in the improvement on cancer patients outcomes. The public ceremony, chaired by the Spanish Queen Letizia and the president of AECC, reviewed the position of Spanish research in the cancer field in Europe.
Later on, there was a private ceremony in which all the awardees were offered a personalised commemorative painting by the main representatives of the AECC.
The new academic year starts and the lab is full of people!! (well, at least it feels full for Bea and I… 😉 )From left to right: Bea (you know her already 🙂 ); Jose , our new technician; Sarah, our postdoc, and Lorena, our visiting PhD student from Prof. Giuseppe Gasparre´s group in Bologne.