We offer an exciting PhD project for the INPhINIT PhD fellowships programme from “La Caixa” Foundation. The phylosophy of the programme is the attraction of outstanding students of any nationality for a PhD in Spain or Portugal, offering them an integral formative programme in centres of research excellence.
The candidate will join a young and vibrant
research group devoted to the study of pancreatic cancer metabolism, focusing
on CSC-targeting therapeutic strategies. The present project involves the study
of the role of lipid storage and mobilization for CSCs adaptation to the
changing and challenging conditions characteristic of tumor progression and
metastasis. We aim to analyze the specific role of lipid uptake, storage and
mobilization for tumor progression in order to identify and validate the most
effective and readily translatable CSC-targeting strategies. For that purpose,
the candidate will work with PDAC patient-derived material from solid and
liquid biopsies both in vitro and in vivo.
The candidate will use a broad range of
cellular and molecular biology techniques, including 3D cultures of
tumor-derived cells, co-culture with stromal cells, isolation of rare
subpopulations by FACS sorting and metabolic/metabolomics assays, as well as in
vivo experiments involving tumorigenicity and metastasis assays. We are
currently collaborating with 2 different groups located in the UK, so
opportunities for short stages in those labs will be available during the
completion of the PhD.
Desired skills of the candidates are: MSc in
any Biomedicine-related discipline, knowledge of basic cellular and molecular
techniques, knowledge of cellular metabolism, and experience in cancer
We were invited to the AECC 2019 Award Ceremony to officially receive the Worldwide Award. This ceremony takes place every year on September 24th, the World Cancer Research Day, to acknowledge the role of scientific research in the improvement on cancer patients outcomes. The public ceremony, chaired by the Spanish Queen Letizia and the president of AECC, reviewed the position of Spanish research in the cancer field in Europe.
Later on, there was a private ceremony in which all the awardees were offered a personalised commemorative painting by the main representatives of the AECC.
The new academic year starts and the lab is full of people!! (well, at least it feels full for Bea and I… 😉 )From left to right: Bea (you know her already 🙂 ); Jose , our new technician; Sarah, our postdoc, and Lorena, our visiting PhD student from Prof. Giuseppe Gasparre´s group in Bologne.
Since our WCR grant is finally official, our communication department made a great job diffusing the news everywhere!! We have been featured in newspapers, radio and even TV! It was a great experience and an amazing opportunity to make the project known for general public.
We are upgrading our lab webpage, it will be ready very soon!! We would like to share with you our research as well as related news and publications… Join us if you want to know more about the world of cancer stem cells and tumoral metabolism!